Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.70 |
| ▸ | F10 | P00742 | 1/20 | 0.70 |
| ▸ | F12 | P00748 | 1/20 | 0.70 |
| ▸ | F7 | P08709 | 1/20 | 0.70 |
| ▸ | F3 | P13726 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | C1S | P09871 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamidoxime SCHEMBL102483 | 0.89 | KMT2A (0.58) | F2F10F12F7F3 | |
| SCHEMBL22872296 | 0.89 | KMT2A (0.58) | F2F10F12F7F3 | |
| Benzamidoxime SCHEMBL30242 | 0.89 | KMT2A (0.58) | F2F10F12F7F3 | |
| Benzamidoxime SCHEMBL872652 | 0.89 | KMT2A (0.58) | F2F10F12F7F3 | |
| Benzamidoxime SCHEMBL4293941 | 0.86 | F2 (0.52) | F2F10F12F7F3 | |
| Benzamidoxime SCHEMBL27457742 | 0.86 | POLB (0.58) | F2F10F12F7F3 | |
| Benzamidoxime SCHEMBL9211538 | 0.86 | KMT2A (0.56) | F2F10F12F7F3 | |
| Benzamidine SCHEMBL23067876 | 0.83 | F2 (1.00) | F2F10F12F7F3 | |
| Benzamidine SCHEMBL9207 | 0.83 | — | — | |
| SCHEMBL18557033 | 0.83 | F2 (1.00) | F2F10F12F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101951897-B | Amidoxim carboxylate and N-hydroxyl guanidine carboxylate are for the preparation of the purposes of prodrug | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2016-01-20 | — | — | CN | disclosed |
| CN-101951897-A | Use of amidoxime carboxylic acid esters and N-hydroxyguanidine carboxylic acid esters for producing prodrugs | DRITTE PATENTPORTFOLIO BETEILI | 2011-01-19 | — | — | CN | disclosed |