Benzamidoxime

Benzamidoxime

SCHEMBL4293941

N=C(N)c1ccccc1.NC(=NO)c1ccccc1.ON=C(NO)c1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.52
F10 P00742 1/20 0.52
F12 P00748 1/20 0.52
F7 P08709 1/20 0.52
F3 P13726 1/20 0.52
PKM P14618 1/20 0.52
BLM P54132 1/20 0.50
PRSS1 P07477 3/20 0.48
PRSS2 P07478 3/20 0.48
PRSS3 P35030 3/20 0.48
KMT2A Q03164 2/20 0.48
C1S P09871 2/20 0.48
RECQL P46063 1/20 0.48
WDR5 P61964 1/20 0.42
MEN1 O00255 1/20 0.38
KDM1A O60341 1/20 0.37
CYP2C19 P33261 2/20 0.36
GAA P10253 2/20 0.36
POLB P06746 1/20 0.36
NQO2 P16083 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamidoxime SCHEMBL27799692 0.86 F2 (0.70) F2F10F12F7F3
SCHEMBL3942966 0.80 IDO1 (0.46) KMT2AMEN1CYP2C19GAAHDAC1
SCHEMBL134570 0.80 IDO1 (0.46) KMT2AMEN1CYP2C19GAAHDAC1
Benzamidoxime SCHEMBL872652 0.76 KMT2A (0.58) F2F10F12F7F3
SCHEMBL22872296 0.76 KMT2A (0.58) F2F10F12F7F3
Benzamidoxime SCHEMBL30242 0.76 KMT2A (0.58) F2F10F12F7F3
Benzamidoxime SCHEMBL102483 0.76 KMT2A (0.58) F2F10F12F7F3
Benzamidoxime SCHEMBL27457742 0.74 POLB (0.58) F2F10F12F7F3
Benzamidoxime SCHEMBL9211538 0.74 KMT2A (0.56) F2F10F12F7F3
Benzamidine SCHEMBL23067876 0.72 F2 (1.00) F2F10F12F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090270440-A1 BIOAVAILABILITY OF ACTIVE SUBSTANCES HAVING AN AMIDINE FUNCTION IN MEDICAMENTS DRITE PATENTPORTFOLIO BETEILLIGUNGSGESELLSCHAFT MBH & CO. KG (DE) 2009-10-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270440-A1 BIOAVAILABILITY OF ACTIVE SUBSTANCES HAVING AN AMIDINE FUNCTION IN MEDICAMENTS HNMT, SLC7A1, HRH4 F2 1980/4885F10 4407/4885F12 2512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.