Benzamidoxime

Benzamidoxime

SCHEMBL30242

N/C(=N\O)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
GAA P10253 3/20 0.54
POLB P06746 2/20 0.54
CYP2C19 P33261 2/20 0.54
GRIN1 Q05586 2/20 0.52
GRIN2B Q13224 2/20 0.52
KDM1A O60341 3/20 0.48
BLM P54132 2/20 0.48
RECQL P46063 2/20 0.48
F2 P00734 1/20 0.48
F10 P00742 1/20 0.48
F12 P00748 1/20 0.48
F7 P08709 1/20 0.48
F3 P13726 1/20 0.48
PKM P14618 1/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamidoxime SCHEMBL102483 1.00 KMT2A (0.58) KMT2AMEN1GAAPOLBCYP2C19
SCHEMBL22872296 1.00 KMT2A (0.58) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL872652 1.00 KMT2A (0.58) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL9211538 0.97 KMT2A (0.56) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL27457742 0.97 POLB (0.58) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL23405829 0.91 CYP2C19 (0.52) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL28695169 0.91 CYP2C19 (0.57) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL10502994 0.91 MEN1 (0.50) KMT2AMEN1GAAPOLBCYP2C19
SCHEMBL21215226 0.89 GFER (0.55) KMT2AMEN1GAAPOLBCYP2C19
Benzamidoxime SCHEMBL27799692 0.89 F2 (0.70) KMT2AMEN1GAAPOLBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12172972-B1 3-(3-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-12-24 US claimed
US-12162845-B1 3-(4-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-12-10 US claimed
US-11958816-B1 N′-({[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl}oxy)benzenecarboximidamide as an antimicrobial compound King Faisal University (SA) 2024-04-16 US claimed
US-11958814-B1 3-(4-nitrophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-04-16 US claimed
US-11919871-B1 3-(3-chlorophenyl)-5-((2-isopropyl-5- methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-03-05 US claimed
CN-113662938-B Application of amine derivative in preparation of anti-tumor pharmaceutical composition 广西科技大学 2022-08-16 CN claimed
CN-113662938-A Application of amine derivative in preparation of anti-tumor pharmaceutical composition 广西科技大学 2021-11-19 CN claimed
CN-110156769-B Compound with xanthine oxidase inhibitory activity and preparation method and application thereof 沈阳海诺威医药科技有限公司 2020-08-21 CN claimed
US-20120028955-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY 2012-02-02 US claimed
US-20120028956-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY 2012-02-02 US claimed
US-20090270362-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY 2009-10-29 US claimed
US-20090130849-A1 CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE EKC TECHNOLOGY, INC. 2009-05-21 US claimed
WO-2009058274-A1 CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE EKC TECHNOLOGY, INC. (US) 2009-05-07 WO claimed
US-20090111965-A1 NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION EKC TECHNOLOGY, INC. 2009-04-30 US claimed
US-20260042731-A1 (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS CORTEVA AGRISCIENCE LLC (US) 2026-02-12 US disclosed
WO-2025224512-A1 NOVEL COMPOUND AS 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 (HSD17B13) INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2025-10-30 WO disclosed
US-12275723-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2025-04-15 US disclosed
US-20040220238-A1 Pyrrolidine oxadiazole-and thiadiazole derivatives MERCK SERONO SA (CH) 2004-11-04 US disclosed
WO-2004058254-A1 HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS PHARMACIA CORPORATION (US) 2004-07-15 WO disclosed
WO-1997008150-A1 SUBSTITUTED CYCLIC UREAS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958816-B1 N′-({[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl}oxy)benzenecarboximidamide as an antimicrobial compound AADAC, B3GNT2, OGA KMT2A 3234/4885MEN1 4772/4885GAA 1484/4885
US-20040220238-A1 Pyrrolidine oxadiazole-and thiadiazole derivatives OXTR, PRLHR, PGF KMT2A 4449/4885MEN1 4838/4885GAA 4875/4885
US-20120028955-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME GRM5, GRIK5, GRM1 KMT2A 1153/4885MEN1 4490/4885GAA 3385/4885
US-12275723-B2 Compounds and uses thereof NLN, ACHE, CLN6 KMT2A 2479/4885MEN1 1807/4885GAA 67/4885
US-11919871-B1 3-(3-chlorophenyl)-5-((2-isopropyl-5- methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 KMT2A 2864/4885MEN1 2592/4885GAA 3929/4885
US-20120028956-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME GRM5, GRIK5, GRM1 KMT2A 1153/4885MEN1 4490/4885GAA 3385/4885
US-12172972-B1 3-(3-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 KMT2A 2903/4885MEN1 2183/4885GAA 3924/4885
US-12162845-B1 3-(4-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 KMT2A 2752/4885MEN1 2212/4885GAA 3988/4885
US-20260042731-A1 (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS DDT, AADAC, HACL2 KMT2A 2330/4885MEN1 1993/4885GAA 1702/4885
US-11958814-B1 3-(4-nitrophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 KMT2A 3045/4885MEN1 2744/4885GAA 3543/4885
US-20090111965-A1 NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION GNMT, NIT2, NNMT KMT2A 1813/4885MEN1 1958/4885GAA 2484/4885
US-20090270362-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME GRM5, GRIK5, GRM1 KMT2A 1153/4885MEN1 4490/4885GAA 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.