Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050332 | 0.85 | ALDH1A1 (0.38) | CA14HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL30772730 | 0.83 | CA14 (0.39) | CA14HDAC6HDAC1HDAC2MAOA | |
| SCHEMBL27826887 | 0.83 | HDAC6 (0.39) | CA14HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL15918864 | 0.82 | TSHR (0.33) | TSHRMAPT | |
| SCHEMBL13109092 | 0.81 | HDAC6 (0.38) | CA14HDAC6HDAC1HDAC2MAOA | |
| SCHEMBL17267525 | 0.81 | CTSK (0.40) | CA14HDAC6HDAC1HDAC2MAOA | |
| SCHEMBL30324896 | 0.81 | HDAC6 (0.38) | CA14HDAC6HDAC1HDAC2MAOA | |
| SCHEMBL1884648 | 0.81 | CA14 (0.40) | CA14HDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL20053155 | 0.80 | CTSK (0.39) | CA14HDAC6HDAC1HDAC2MAOA | |
| SCHEMBL12283396 | 0.80 | CTSK (0.39) | CA14HDAC6HDAC1HDAC2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959887-B | Pyrrolopyridines as kinase inhibitors | ARRAY BIOPHARMA INC | 2013-07-31 | — | — | CN | disclosed |
| CN-101959887-A | Pyrrolopyridine as kinase inhibitor | ARRAY BIOPHARMA INC | 2011-01-26 | — | — | CN | disclosed |