Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893441 | 0.98 | KDM4E (0.42) | CYP3A4MAPTKDM4ESSTR3IDO1 | |
| SCHEMBL11039283 | 0.96 | CYP3A4 (0.43) | CYP3A4MAPTKDM4ESSTR3IDO1 | |
| Bromide SCHEMBL11037477 | 0.94 | CYP3A4 (0.42) | CYP3A4MAPTKDM4ESSTR3IDO1 | |
| SCHEMBL27890446 | 0.92 | CYP3A4 (0.46) | CYP3A4MAPTKDM4EIDO1MEN1 | |
| SCHEMBL4604214 | 0.83 | TACR1 (0.44) | CYP3A4MAPTKDM4ESSTR3IDO1 | |
| SCHEMBL22857018 | 0.82 | MC4R (0.44) | CYP3A4MAPTKDM4EOPRM1 | |
| SCHEMBL7500962 | 0.81 | CYP3A4 (0.43) | CYP3A4MAPTKDM4ESSTR3TSHR | |
| SCHEMBL27820512 | 0.81 | ATM (0.48) | CYP3A4MAPTSSTR3IDO1MEN1 | |
| SCHEMBL2661298 | 0.79 | TAAR1 (0.47) | CYP3A4MAPTSSTR3IDO1TSHR | |
| SCHEMBL4191813 | 0.79 | CYP3A4 (0.54) | CYP3A4MEN1KMT2ATSHROPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104093758-B | Shelf life of halogenated olefin-containing polyol blends improved by encapsulation of active ingredients | 阿科玛股份有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106397708-A | Improved shelf life of polyol blends containing halogenated olefins by encapsulation of active components | 阿科玛股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-104093758-A | Shelf life of halogenated olefin-containing polyol blends improved by encapsulation of active ingredients | ARKEMA INC | 2014-10-08 | — | — | CN | claimed |
| CN-101896525-B | Stabilization of polyurethane foam polyol premixes containing halogenated olefin blowing agents | HONEYWELL INT INC | 2014-06-18 | — | — | CN | claimed |
| CN-101896525-A | Stabilization of polyurethane foam polyol premixes containing halogenated olefin blowing agents | HONEYWELL INT INC | 2010-11-24 | — | — | CN | claimed |
| CN-110234672-A | PU formulation comprising HFO | 巴斯夫欧洲公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-109476979-A | Polyol premixes with improved shelf life | 阿科玛股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-106046411-B | The improved stability of polyurethane polyol blend comprising halogenated olefin blowing agents | 阿科玛股份有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-107949614-A | Adhesion agent composition and its manufacture method and adhesive film | 三井化学东赛璐株式会社 | 2018-04-20 | — | — | CN | disclosed |
| CN-104685021-B | The improved stability of polyurethane polyol blend comprising halogenated olefin blowing agents | 阿科玛股份有限公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-106750482-A | The stability of the improvement of the polyurethane polyol blend comprising halogenated olefin blowing agents | 阿科玛股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106750490-A | For the tetrafluoro butylene foaming agent of polyurethane foam | 阿科玛股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-103415548-A | Improved Stability of Polyurethane Polyol Blends Containing Halogenated Olefin Blowing Agents | ARKEMA INC | 2013-11-27 | — | — | CN | disclosed |
| CN-103415543-A | Improved Stability of Polyurethane Polyol Blends Containing Halogenated Olefin Blowing Agents | ARKEMA INC | 2013-11-27 | — | — | CN | disclosed |
| CN-102858829-A | Method for Improving the Stability of Polyurethane Polyol Blends Containing Halogenated Olefin Blowing Agents | ARKEMA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-102575046-A | Tetrafluorobutene blowing agent compositions for polyurethane foams | ARKEMA INC | 2012-07-11 | — | — | CN | disclosed |
| CN-102498237-A | Improved polyurethane foaming processes and foam properties using halogenated olefin blowing agent | ARKEMA INC | 2012-06-13 | — | — | CN | disclosed |
| CN-102159634-A | Hfo-1234ze mixed isomers with hfc-245fa as a blowing agent, aerosol, and solvent | HONEYWELL INT INC | 2011-08-17 | — | — | CN | disclosed |
| CN-101952336-A | Amine catalysts for polyurethane foams | HONEYWELL INT INC | 2011-01-19 | — | — | CN | disclosed |
| CN-101896525-A | Stabilization of polyurethane foam polyol premixes containing halogenated olefin blowing agents | HONEYWELL INT INC | 2010-11-24 | — | — | CN | disclosed |