Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.55 |
| ▸ | ITGAL | P20701 | 5/20 | 0.55 |
| ▸ | JAK2 | O60674 | 3/20 | 0.49 |
| ▸ | JAK3 | P52333 | 3/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856595 | 0.83 | CDK9 (0.52) | ITGB2ICAM1ITGALGAKFPR2 | |
| SCHEMBL27873347 | 0.83 | CDK9 (0.52) | ITGB2ICAM1ITGALGAKFPR2 | |
| SCHEMBL28789718 | 0.82 | NEK2 (0.44) | ITGB2ICAM1ITGALJAK2JAK3 | |
| SCHEMBL28785976 | 0.82 | ITGB2 (0.49) | ITGB2ICAM1ITGALJAK2JAK3 | |
| SCHEMBL28785974 | 0.81 | RPS6KB1 (0.43) | ITGB2ICAM1ITGALRPS6KB1AKT1 | |
| SCHEMBL21434097 | 0.79 | ITGB2 (0.56) | ITGB2ICAM1ITGALJAK2JAK3 | |
| SCHEMBL21433911 | 0.77 | ITGB2 (0.51) | ITGB2ICAM1ITGALJAK2JAK3 | |
| SCHEMBL21433961 | 0.76 | ITGB2 (0.54) | ITGB2ICAM1ITGALJAK2JAK3 | |
| SCHEMBL21434031 | 0.73 | ITGB2 (0.55) | ITGB2ICAM1ITGALJAK2JAK3 | |
| SCHEMBL21433974 | 0.73 | ITGB2 (0.54) | ITGB2ICAM1ITGALJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101889004-A | Protein kinase inhibitors | INGENIUM PHARMACEUTICALS GMBH | 2010-11-17 | — | — | CN | disclosed |