Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.72 |
| ▸ | EDNRA | P25101 | 4/20 | 0.72 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844570 | 0.92 | AGTR1 (0.72) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL2779288 | 0.92 | AGTR1 (0.72) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL25084308 | 0.91 | AGTR1 (0.77) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL27418021 | 0.90 | AGTR1 (0.73) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL27425080 | 0.89 | AGTR1 (0.74) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL21755938 | 0.88 | AGTR1 (0.68) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL27418080 | 0.88 | AGTR1 (0.70) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL27418603 | 0.88 | AGTR1 (0.70) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL27420915 | 0.88 | AGTR2 (0.74) | AGTR1EDNRAAGTR2LTB4R2ACHE | |
| SCHEMBL25084203 | 0.87 | AGTR1 (0.70) | AGTR1EDNRAAGTR2LTB4R2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135350-A2 | BIPHENYL INTERMEDIATE COMPOUNDS AND METHODS FOR THE PREPARATION OF A DUAL ANGIOTENSIN II AND ENDOTHELIN A RECEPTOR ANTAGONIST | PHARMACOPEIA, LLC (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010135350-A2 | BIPHENYL INTERMEDIATE COMPOUNDS AND METHODS FOR THE PREPARATION OF A DUAL ANGIOTENSIN II AND ENDOTHELIN A RECEPTOR ANTAGONIST | PHARMACOPEIA, LLC (US) | 2010-11-25 | — | — | WO | disclosed |