Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.45 |
| ▸ | HNF4A | P41235 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27802752 | 0.85 | HPGD (0.45) | IKBKBCHUKACLYCA1CA2 | |
| SCHEMBL27823359 | 0.84 | PTPN1 (0.45) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL27786187 | 0.82 | PTPN1 (0.58) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL7057448 | 0.80 | ACMSD (0.56) | ACMSDHNF4ADHFRMCL1ACLY | |
| SCHEMBL4969546 | 0.78 | ALDH1A1 (0.43) | AKR1C2AKR1C1MCL1CA1CA2 | |
| SCHEMBL14784538 | 0.78 | PTPN1 (0.53) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL5544778 | 0.76 | ALDH1A1 (0.42) | AKR1C2AKR1C1MCL1PTGER4CA1 | |
| SCHEMBL3467831 | 0.76 | PTPN1 (0.51) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL27846422 | 0.75 | KMT2A (0.59) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL27827712 | 0.75 | PTPN1 (0.50) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981003-B | Amide compounds, compositions and uses thereof | RENOVIS INC | 2014-07-02 | — | — | CN | claimed |
| CN-101981003-A | Amide compounds, compositions and uses thereof | RENOVIS INC | 2011-02-23 | — | — | CN | claimed |
| CN-101981003-B | Amide compounds, compositions and uses thereof | RENOVIS INC | 2014-07-02 | — | — | CN | disclosed |
| CN-101981003-A | Amide compounds, compositions and uses thereof | RENOVIS INC | 2011-02-23 | — | — | CN | disclosed |