Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051898 | 0.88 | RECQL (0.50) | ALDH1A1RECQLMMP8BLMSMN1; SMN2 | |
| SCHEMBL6051878 | 0.86 | ALDH1A1 (0.51) | ALDH1A1RECQLMMP8BLMEPHX2 | |
| SCHEMBL28168069 | 0.86 | ALDH1A1 (0.67) | ALDH1A1RECQLMMP8SMN1; SMN2HIF1A | |
| SCHEMBL6051877 | 0.85 | ALDH1A1 (0.50) | ALDH1A1RECQLMMP8BLMSMN1; SMN2 | |
| SCHEMBL339395 | 0.83 | ALDH1A1 (0.56) | ALDH1A1RECQLMMP8SMN1; SMN2TSHR | |
| SCHEMBL4065071 | 0.81 | ALDH1A1 (0.50) | ALDH1A1RECQLMMP8FDPSTSHR | |
| SCHEMBL6361552 | 0.81 | ALDH1A1 (0.47) | ALDH1A1RECQLMMP8EPHX2ACACB | |
| SCHEMBL6160783 | 0.81 | ALDH1A1 (0.47) | ALDH1A1RECQLMMP8EPHX2TDP1 | |
| SCHEMBL6782409 | 0.80 | ALDH1A1 (0.76) | ALDH1A1RECQLMMP8TSHRMAPK1 | |
| SCHEMBL9001364 | 0.78 | TSHR (0.45) | ALDH1A1RECQLMMP8FDPSEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248901-A1 | Streptogramines and method for preparing same by mutasynthesis | Aventis Pharma S.A. (FR) | 2010-11-10 | — | — | EP | disclosed |
| EP-0770132-B1 | NEW STREPTOGRAMINES | AVENTIS PHARMA SA (FR) | 2010-09-08 | — | — | EP | disclosed |
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | disclosed |