Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870117 | 0.86 | ALDH1A1 (0.69) | ALDH1A1RECQLMMP8TSHRHTT | |
| SCHEMBL28168069 | 0.84 | ALDH1A1 (0.67) | ALDH1A1RECQLMMP8RAB9AMAPT | |
| SCHEMBL30801043 | 0.81 | FDPS (0.52) | ALDH1A1RECQLMMP8FDPSHTT | |
| SCHEMBL6191319 | 0.81 | FDPS (0.52) | ALDH1A1RECQLMMP8FDPSHTT | |
| SCHEMBL2780432 | 0.81 | ALDH1A1 (0.51) | ALDH1A1RECQLMMP8TSHRFDPS | |
| SCHEMBL6051878 | 0.81 | ALDH1A1 (0.51) | ALDH1A1RECQLMMP8TSHRPOLB | |
| SCHEMBL5496699 | 0.80 | ALDH1A1 (0.74) | ALDH1A1RECQLMMP8TSHRHTT | |
| SCHEMBL6051898 | 0.80 | RECQL (0.50) | ALDH1A1RECQLMMP8TSHRCYP3A4 | |
| SCHEMBL6051877 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RECQLMMP8RAB9APOLB | |
| SCHEMBL6501640 | 0.79 | ACACB (0.49) | ALDH1A1RECQLTSHRRAB9AFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450750-B1 | USE OF 2-AMINO-4-PYRIDYLMETHYL-THIAZOLINE DERIVATIVES AS INHIBITORS OF INDUCIBLE NO-SYNTHASE | AVENTIS PHARMA SA (FR) | 2009-10-21 | — | — | EP | disclosed |
| EP-1450750-A2 | USE OF 2-AMINO-4-PYRIDYLMETHYL-THIAZOLINE DERIVATIVES AS INHIBITORS OF INDUCIBLE NO-SYNTHASE | Aventis Pharma S.A. (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003039446-A2 | USE OF 2-AMINO-4-PYRIDYLMETHYL-THIAZOLINE DERIVATIVES AS INHIBITORS OF INDUCIBLE NO-SYNTHASE | AVENTIS PHARMA S.A. (FR) | 2003-05-15 | — | — | WO | disclosed |