Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204087 | 0.84 | CA12 (0.50) | KMT2AL3MBTL1ALDH1A1APAF1MAPT | |
| SCHEMBL3244639 | 0.84 | POLB (0.50) | KMT2AALDH1A1TTRCYP2C19EYA3 | |
| SCHEMBL1398779 | 0.76 | CYP2C19 (0.63) | KMT2AL3MBTL1ALDH1A1APAF1MAPT | |
| SCHEMBL3612485 | 0.74 | EDNRA (0.66) | KMT2AL3MBTL1ALDH1A1MAPTRAB9A | |
| SCHEMBL11732540 | 0.74 | KDM4E (0.45) | KMT2AALDH1A1MAPTTTRCYP2C19 | |
| SCHEMBL31604813 | 0.74 | CYP2C19 (0.43) | KMT2ASLC26A4CYP2C19EYA3MEN1 | |
| SCHEMBL355272 | 0.73 | TDP1 (0.61) | KMT2AL3MBTL1ALDH1A1TDP1MCL1 | |
| SCHEMBL12610891 | 0.72 | KMT2A (0.52) | KMT2AALDH1A1MAPTHTTMCL1 | |
| SCHEMBL9760981 | 0.71 | CYP2C9 (0.66) | KMT2AALDH1A1MAPTHTTRAB9A | |
| SCHEMBL28849644 | 0.71 | EDNRA (0.50) | KMT2AALDH1A1MAPTRAB9ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-105209444-B | It can be used as the benzo-fused heterocycle derivative of GPR120 activator | 詹森药业有限公司 | 2017-12-29 | — | — | CN | disclosed |
| CN-102083827-A | Thiazolidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-06-01 | — | — | CN | disclosed |
| CN-101730696-A | 3-aza-bicyclo [3.3.0] octane compounds | ACTELION PHARMACEUTICALS LTD | 2010-06-09 | — | — | CN | disclosed |