Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.54 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.54 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398779 | 0.87 | CYP2C19 (0.63) | CYP2C9CYP2C19EYA3TTRKDM4E | |
| SCHEMBL15346066 | 0.86 | CYP2C9 (0.66) | CYP2C9CYP2C19EYA3KDM4EALDH1A1 | |
| SCHEMBL1772596 | 0.82 | CYP2C9 (0.64) | CYP2C9CYP2C19EYA3KDM4EALDH1A1 | |
| SCHEMBL11360558 | 0.81 | KDM4E (0.53) | CYP2C9TTRKDM4EALDH1A1MAPT | |
| SCHEMBL31217554 | 0.80 | ALDH1A1 (0.64) | CYP2C9CYP2C19KDM4EALDH1A1MAPT | |
| SCHEMBL11881228 | 0.79 | ALDH1A1 (0.61) | CYP2C9CYP2C19KDM4EALDH1A1MAPT | |
| SCHEMBL9760347 | 0.79 | CYP2C9 (0.68) | CYP2C9CYP2C19EYA3TTRALDH1A1 | |
| SCHEMBL6527669 | 0.78 | ALDH1A1 (0.69) | CYP2C9CYP2C19TTRKDM4EALDH1A1 | |
| SCHEMBL28245008 | 0.77 | CYP2C19 (0.79) | CYP2C9CYP2C19EYA3ALDH1A1MAPT | |
| SCHEMBL4757017 | 0.77 | LMNA (0.61) | CYP2C9KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3206006-A | — | — | None | — | — | JP | disclosed |
| US-20170022165-A1 | PQSR MODULATORS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
| JP-H03206006-A | NEW PLANT GROWTH INHIBITOR | DAICEL CHEM IND LTD | 1991-09-09 | — | — | JP | disclosed |
| US-3937837-A | SUBSTITUTED CHROMONE-3-CARBONITRILES, CARBOXAMIDES AND CARBOXYLIC ACIDS USEFUL FOR PREVENTING ASTHMATIC SYMPTOMS | WARNER-LAMBERT COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022165-A1 | PQSR MODULATORS | QARS1, SRPRA, MRPS35 | CYP2C9 2135/4885CYP2C19 1382/4885EYA3 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.