Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082614 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1POLBGAAHTT | |
| SCHEMBL15081285 | 0.84 | ALDH1A1 (0.45) | ALDH1A1POLBGAAHTTKMT2A | |
| SCHEMBL30353758 | 0.84 | ALDH1A1 (0.45) | ALDH1A1POLBGAAHTTKMT2A | |
| SCHEMBL24723054 | 0.83 | PDGFRB (0.45) | ALDH1A1TDP1POLBGAAHTT | |
| SCHEMBL5970965 | 0.83 | GPR35 (0.54) | ALDH1A1TDP1POLBGAAHTT | |
| SCHEMBL18878093 | 0.83 | KMT2A (0.46) | ALDH1A1TDP1POLBGAAHTT | |
| SCHEMBL5219938 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1POLBHTTMAPK1 | |
| SCHEMBL27763193 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAAHTTMAPK1NPSR1 | |
| SCHEMBL22866318 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TDP1POLBGAAHTT | |
| SCHEMBL11510888 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1POLBGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101983384-A | Prolyl hydroxylase inhibitors | SMITHKLINE BEECHAM CORP | 2011-03-02 | — | — | CN | disclosed |