SCHEMBL27804385

SCHEMBL27804385

CCOS(=O)(=O)c1ccccc1F.[NaH]

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
PSIP1 O75475 1/20 0.41
KAT6A Q92794 7/20 0.39
HCRTR2 O43614 1/20 0.39
KCNA5 P22460 1/20 0.38
HTR6 P50406 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HSD11B1 P28845 1/20 0.36
GBA1 P04062 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27828198 0.98 TSHR (0.44) TSHRKMT2ATDP1MEN1NPC1
SCHEMBL29415266 0.84 GAA (0.39) TSHRKMT2ATDP1MEN1PSIP1
SCHEMBL778991 0.84 GAA (0.39) TSHRKMT2ATDP1MEN1PSIP1
SCHEMBL8712194 0.81 HSD11B1 (0.43) TSHRHCRTR2HTR6ALDH1A1HSD11B1
SCHEMBL8521555 0.80 TSHR (0.43) TSHRKMT2ATDP1KAT6AALDH1A1
SCHEMBL27937639 0.79 GAA (0.52) RAB9AHTR6ALDH1A1
SCHEMBL27937613 0.78 GAA (0.50) RAB9AHTR6ALDH1A1
SCHEMBL582357 0.77 KMT2A (0.44) KMT2AMEN1HCRTR2HTR6ALDH1A1
SCHEMBL8779870 0.77 GAA (0.54) RAB9AHTR6ALDH1A1
SCHEMBL2906066 0.77 CTSB (0.47) TSHRKMT2AMEN1PSIP1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101750888-A Photoacid generator, copolymer, chemically amplified resist composition, and method of forming pattern using the chemically amplified resist composition KOREA KUMHO PETROCHEM CO LTD 2010-06-23 CN disclosed