Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | CPA1 | P15085 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780445 | 1.00 | LMNA (0.54) | LMNATDP1MMEMMP2MMP9 | |
| SCHEMBL157547 | 0.91 | MME (0.61) | MMEMMP2MMP9L3MBTL1ADAMTS4 | |
| SCHEMBL29601051 | 0.88 | LMNA (0.52) | LMNATDP1MMEMMP2MMP9 | |
| SCHEMBL2779696 | 0.86 | ACE (0.46) | LMNATDP1MMEACECPA1 | |
| SCHEMBL28286750 | 0.86 | MME (0.62) | LMNATDP1MMEMMP2MMP9 | |
| SCHEMBL25284015 | 0.86 | MME (0.62) | LMNATDP1MMEMMP2MMP9 | |
| SCHEMBL2779693 | 0.86 | ACE (0.46) | LMNATDP1MMEACECPA1 | |
| SCHEMBL30411925 | 0.85 | LMNA (0.50) | LMNATDP1MMEMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6775146 | 0.85 | ACE (0.44) | LMNATDP1MMEACECPA1 | |
| SCHEMBL9178000 | 0.84 | MME (0.54) | LMNATDP1MMEMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248901-A1 | Streptogramines and method for preparing same by mutasynthesis | Aventis Pharma S.A. (FR) | 2010-11-10 | — | — | EP | disclosed |
| EP-0770132-B1 | NEW STREPTOGRAMINES | AVENTIS PHARMA SA (FR) | 2010-09-08 | — | — | EP | disclosed |