Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16815749 | 0.78 | POLB (0.52) | KDM5AKDM4CKDM5BKDM2BPOLB | |
| SCHEMBL23116885 | 0.78 | POLB (0.52) | POLBHSP90AA1CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL1906019 | 0.78 | POLB (0.52) | POLBCYP2C9CYP2C8CYP2C19CYP2C18 | |
| SCHEMBL2987627 | 0.76 | POLB (0.48) | KDM5AKDM4CKDM5BKDM2BPOLB | |
| SCHEMBL4859521 | 0.76 | POLB (0.48) | KDM5AKDM4CKDM5BPOLBCYP2C9 | |
| SCHEMBL7757122 | 0.74 | KDM5A (0.43) | KDM5AKDM4CKDM5BKDM2BCALM1 | |
| SCHEMBL27239129 | 0.74 | POLB (0.47) | POLBCYP2C9CYP2C8CYP2C19CYP2C18 | |
| SCHEMBL27323137 | 0.74 | POLB (0.47) | POLBHSP90AA1CYP2C9CYP2C19MDM2 | |
| SCHEMBL7109626 | 0.74 | POLB (0.47) | KDM5AKDM4CKDM5BKDM2BPOLB | |
| SCHEMBL2596939 | 0.72 | KDM5A (0.41) | KDM5AKDM4CKDM5BKDM2BCALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687809-A | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI AVENTIS | 2010-03-31 | — | — | CN | claimed |