SCHEMBL2987627

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16815749	0.85	POLB (0.52)	POLBKDM5AKDM4CKDM5BCYP2C18
	SCHEMBL4859521	0.81	POLB (0.48)	POLBKDM5AKDM4CKDM5BCYP2C18
	SCHEMBL1195187	0.81	NPC1 (0.50)	POLBKDM5AKDM4CKDM5BALDH1A1
	SCHEMBL21357888	0.78	LTA4H (0.47)	KDM5AKDM4CKDM5BTDP1CYP2C18
	SCHEMBL23116885	0.77	POLB (0.52)	POLBTDP1CYP2C18ALDH1A1CYP2C9
	SCHEMBL1906019	0.77	POLB (0.52)	POLBCYP2C18CYP2C8ALDH1A1CYP2C9
	SCHEMBL7109626	0.76	POLB (0.47)	POLBKDM5AKDM4CKDM5BALDH1A1
	SCHEMBL9804062	0.76	POLB (0.43)	POLBKDM5AKDM4CKDM5BALDH1A1
	SCHEMBL1195389	0.75	TSHR (0.56)	KDM5AKDM4CKDM5BALDH1A1GLS
	SCHEMBL5579308	0.74	POLB (0.57)	POLBTDP1CYP2C18CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.