Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938186 | 0.82 | GPR52 (0.47) | KDM5AKDM4CKDM5BGPR52CYP19A1 | |
| SCHEMBL332470 | 0.81 | DRD4 (0.40) | CYP19A1ALDH1A1KMT2AL3MBTL1KCNH2 | |
| SCHEMBL16877234 | 0.81 | RAB9A (0.41) | CYP19A1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14938008 | 0.79 | GPR52 (0.44) | GPR52NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL18420442 | 0.79 | KDM4C (0.47) | KDM5AKDM2BKDM4CKDM5BSMN1; SMN2 | |
| SCHEMBL25378900 | 0.78 | DRD4 (0.48) | KDM4CALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21000906 | 0.78 | LTA4H (0.47) | SMN1; SMN2KDM4EALDH1A1LMNAIDH1 | |
| SCHEMBL27539141 | 0.78 | KDM4C (0.52) | KDM5AKDM2BKDM4CKDM5BRAB9A | |
| SCHEMBL2596939 | 0.77 | KDM5A (0.41) | KDM5AKDM2BKDM4CKDM5BCALM1 | |
| SCHEMBL7078697 | 0.76 | DRD4 (0.43) | KDM4CKMT2AL3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233805-B1 | METHYL-1H-PYRAZOLE-ALKYLAMINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2019-02-06 | — | — | EP | disclosed |
| EP-3233805-B1 | METHYL-1H-PYRAZOLE-ALKYLAMINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2019-02-06 | — | — | EP | disclosed |
| EP-0808308-B1 | METHOD FOR SEPARATING CARBINOLS | ESTEVE LABOR DR (ES) | 2001-03-07 | — | — | EP | disclosed |