SCHEMBL27804669

SCHEMBL27804669

[CH2]C(CCCN(C)C)OCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
DNM1 Q05193 3/20 0.36
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823290 0.77 ALDH1A1 (0.39) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL386798 0.77
SCHEMBL24837355 0.76 ALDH1A1 (0.38) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL387318 0.75 OPRM1 (0.44) TSHRDNM1THRB
SCHEMBL13009538 0.74 ALDH1A1 (0.36) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL21906463 0.74 ALDH1A1 (0.36) ALDH1A1TSHRDNM1HTR2AHRH1
SCHEMBL8600839 0.73 OPRM1 (0.42) TSHRDNM1THRB
SCHEMBL7106291 0.73 OPRM1 (0.42) TSHRDNM1THRB
SCHEMBL2448782 0.73 OPRM1 (0.42) TSHRDNM1THRB
SCHEMBL27735170 0.73 OPRM1 (0.42) TSHRDNM1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102924675-A Reduction of aldehydes in amines HUNTSMAN SPEC CHEM CORP 2013-02-13 CN claimed
CN-101977977-A Method for reducing aldehydes in amines HUNTSMAN PETROCHEMICAL LLC 2011-02-16 CN claimed
CN-102924675-B Reduce the method for the aldehyde in amine HUNTSMAN SPEC CHEM CORP. (US) 2015-07-29 CN disclosed
CN-102924675-A Reduction of aldehydes in amines HUNTSMAN SPEC CHEM CORP 2013-02-13 CN disclosed
CN-101977977-A Method for reducing aldehydes in amines HUNTSMAN PETROCHEMICAL LLC 2011-02-16 CN disclosed