Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21709074 | 0.86 | ATM (0.63) | SMN1; SMN2POLBATMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5362227 | 0.78 | POLB (0.70) | SMN1; SMN2POLBATMKDM4EALDH1A1 | |
| SCHEMBL16517998 | 0.78 | POLB (0.47) | SMN1; SMN2POLBATMALDH1A1 | |
| SCHEMBL21709052 | 0.75 | ACHE (0.43) | SMN1; SMN2POLBATMKDM4EALDH1A1 | |
| SCHEMBL1237469 | 0.74 | KDM4E (0.72) | ATMKDM4EGLA | |
| SCHEMBL8145667 | 0.74 | ATM (0.52) | POLBATMKDM4EGLA | |
| SCHEMBL27568728 | 0.73 | ADRB2 (0.53) | KDM4EALDH1A1GLAADRB2ADRB1 | |
| SCHEMBL3984162 | 0.73 | CHRM2 (0.64) | KDM4EALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL5353436 | 0.73 | KDM4E (0.70) | ATMKDM4EGLA | |
| SCHEMBL1239104 | 0.73 | TAAR1 (0.51) | ATMKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |