Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.65 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29148564 | 1.00 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| Bromide SCHEMBL28162997 | 1.00 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| Bromide SCHEMBL31633221 | 1.00 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| SCHEMBL19894632 | 0.98 | ZDHHC20 (0.67) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL29634898 | 0.97 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| Bromide SCHEMBL3043714 | 0.94 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| Bromide SCHEMBL3046686 | 0.94 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2DNM1HTTHSP90AA1 | |
| SCHEMBL5713251 | 0.92 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2DNM1HTTKMT2A | |
| SCHEMBL16799012 | 0.92 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2DNM1HTTKMT2A | |
| SCHEMBL5713293 | 0.92 | ZDHHC20 (0.72) | ZDHHC20ZDHHC2DNM1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903362-A | Low-permeability compact sandstone gas reservoir dewatering lock thickening agent and fracturing fluid | 西南石油大学 | 2024-04-19 | — | — | CN | claimed |
| CN-114907831-B | Temperature response type in-situ phase change fracturing fluid and hydrophobic type in-situ self-generating propping agent | 西南科技大学 | 2023-08-18 | — | — | CN | claimed |
| CN-114907831-A | Temperature response type in-situ phase change fracturing fluid and hydrophobic in-situ self-generated proppant | 西南科技大学 | 2022-08-16 | — | — | CN | claimed |
| EP-2059272-B1 | COATING FORMULATION FOR MEDICAL COATING | DSM IP ASSETS BV (NL) | 2018-02-28 | — | — | EP | claimed |
| US-8178030-B2 | Electrospinning of PTFE with high viscosity materials | ZEUS INDUSTRIAL PRODUCTS, INC. (US) | 2012-05-15 | — | — | US | claimed |
| US-20100076546-A1 | COATING FORMULATION FOR MEDICAL COATING | DSM IP ASSETS B.V. (NL) | 2010-03-25 | — | — | US | claimed |
| EP-2059272-A1 | COATING FORMULATION FOR MEDICAL COATING | DSMIP Assets B.V. (NL) | 2009-05-20 | — | — | EP | claimed |
| WO-2008031596-A1 | COATING FORMULATION FOR MEDICAL COATING | DSM IP ASSETS B.V. (NL) | 2008-03-20 | — | — | WO | claimed |
| US-12270006-B2 | Coating composition, method of making a hydrophilic coating on a substrate, and medical device comprising such coating | DSM IP ASSETS B.V. (NL) | 2025-04-08 | — | — | US | disclosed |
| US-20240206460-A1 | ANTIMICROBIAL SUBSTRATE | GOLDMAN SACHS BDC, INC., AS AGENT | 2024-06-27 | — | — | US | disclosed |
| CN-117903362-A | Low-permeability compact sandstone gas reservoir dewatering lock thickening agent and fracturing fluid | 西南石油大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-114907831-B | Temperature response type in-situ phase change fracturing fluid and hydrophobic type in-situ self-generating propping agent | 西南科技大学 | 2023-08-18 | — | — | CN | disclosed |
| US-20230183596-A1 | Coating composition, method of making a hydrophilic coating on a substrate, and medical device comprising such coating | DSM IP ASSETS B.V. (NL) | 2023-06-15 | — | — | US | disclosed |
| EP-4153645-A1 | COATING COMPOSITION, METHOD OF MAKING A HYDROPHILIC COATING ON A SUBSTRATE, AND MEDICAL DEVICE COMPRISING SUCH COATING | DSM IP Assets B.V. (NL) | 2023-03-29 | — | — | EP | disclosed |
| WO-2007090687-A1 | SHAPE MEMORY MATERIALS COMPRISING POLYELECTROLYTE SEGMENTS | MNEMOSCIENCE GMBH (DE) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007090685-A1 | SHAPE MEMORY POLYMERS AND SHAPE MEMORY POLYMER COMPOSITIONS RESPONSIVE TOWARDS TWO DIFFERENT STIMULI | MNEMOSCIENCE GMBH (DE) | 2007-08-16 | — | — | WO | disclosed |
| EP-1818161-A1 | Shape memory polymers and shape memory polymer compositions responsive towards two different stimuli | Mnemoscience GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1818346-A1 | Shape memory materials comprising polyelectrolyte segments | Mnemoscience GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2007065720-A2 | HYDROPHILIC COATING COMPOSITION FOR URINARY CATHETER | DSM IP ASSETS B.V. (NL) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007065721-A2 | HYDROPHILIC COATING COMPRISING A POLYELECTROLYTE | DSM IP ASSETS B.V. (NL) | 2007-06-14 | — | — | WO | disclosed |