Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.65 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19894632 | 0.98 | ZDHHC20 (0.67) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Bromide SCHEMBL28162997 | 0.97 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Bromide SCHEMBL278071 | 0.97 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Bromide SCHEMBL31633221 | 0.97 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Bromide SCHEMBL29148564 | 0.97 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL2489185 | 0.94 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL3046560 | 0.94 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL11232338 | 0.94 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL28572838 | 0.94 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL8973398 | 0.94 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2HTTDNM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478904-B | Semi-interpenetrating network yin-yang core-shell polymer microsphere profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-114478904-A | Semi-interpenetrating network anion-cation core-shell type polymer microsphere profile control and flooding agent, and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | disclosed |