Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20551984 | 0.77 | PSMB5 (0.47) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL15716272 | 0.77 | PSMB5 (0.47) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL4973401 | 0.76 | MMP9 (0.44) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL4190909 | 0.75 | CA1 (0.43) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL4769827 | 0.75 | MMP9 (0.48) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL12493209 | 0.74 | MMP9 (0.43) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL9045544 | 0.74 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL19597242 | 0.73 | CA1 (0.42) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL3949229 | 0.72 | ATM (0.54) | ATMCA12CA1CA2CA9 | |
| SCHEMBL9013134 | 0.71 | HPGD (0.45) | SLC1A3SLC1A2SLC1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |