Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622211 | 0.84 | CTSL (0.52) | ATMCTSSCTSLCASP3CTSK | |
| SCHEMBL7372298 | 0.83 | ATM (0.61) | ATMCTSSCTSLCTSKCTRB1 | |
| SCHEMBL13737572 | 0.82 | CTSK (0.52) | ATMCTSSCTSLCTSKCA12 | |
| SCHEMBL22775253 | 0.82 | SYK (0.55) | ATMCTSSCTSLCTSKCA12 | |
| SCHEMBL6924287 | 0.82 | LMNA (0.51) | ATMCTSLCASP3CTSKCA1 | |
| SCHEMBL28434500 | 0.82 | CA2 (0.51) | ATMCTSSCTSLCASP3CTSK | |
| SCHEMBL2059541 | 0.82 | ATM (0.62) | ATMCTSSCTSLCTSKCTRB1 | |
| SCHEMBL7303688 | 0.81 | TRPM8 (0.58) | ATMCTSSCTSLCTSKCA12 | |
| SCHEMBL2550712 | 0.81 | CA2 (0.52) | ATMCTSSCTSLCASP3CTSK | |
| SCHEMBL7761195 | 0.81 | ALDH1A1 (0.46) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027679-A1 | PROCESS FOR THE PREPARATION OF GUANIDINO SUBSTITUTED BI-AND POLYPHENYLS THAT ARE SUITABLE AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2009-03-05 | — | — | WO | disclosed |