Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647695 | 0.76 | BCAT2 (0.47) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4243215 | 0.75 | BCAT2 (0.63) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30716388 | 0.73 | BCAT2 (0.61) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL28109352 | 0.73 | PARP1 (0.46) | BCAT2KDM4EALDH1A1CSNK1A1TYRO3 | |
| SCHEMBL30315919 | 0.72 | BCAT2 (0.46) | BCAT2KDM4EALDH1A1DYRK1BMAP2K1 | |
| SCHEMBL16654579 | 0.71 | BCAT2 (0.53) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL210767 | 0.71 | BCAT2 (0.74) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30514077 | 0.71 | BCAT2 (0.74) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL31227695 | 0.71 | CSNK1A1 (0.57) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL997870 | 0.71 | CSNK1A1 (0.57) | BCAT2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712619-A | 5-hydroxypyrimidine-4-carboxamide derivative | DAIICHI SANKYO CO LTD | 2012-10-03 | — | — | CN | disclosed |
| CN-102066337-A | 5-hydroxypyrimidine-4-carboxamide compounds | DAIICHI SANKYO CO LTD | 2011-05-18 | — | — | CN | disclosed |