Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780575 | 0.81 | CNR2 (0.50) | CNR2ANPEPPOLBHDAC1HDAC2 | |
| SCHEMBL13196415 | 0.79 | CNR2 (0.56) | CNR2ANPEPPOLB | |
| SCHEMBL2781759 | 0.79 | CNR2 (0.54) | CNR2ANPEPPOLB | |
| SCHEMBL2779726 | 0.78 | LMNA (0.48) | ANPEP | |
| SCHEMBL2781388 | 0.78 | CNR2 (0.52) | CNR2ANPEPPOLB | |
| SCHEMBL2781067 | 0.74 | CNR2 (0.69) | CNR2ANPEPPOLBHDAC1HDAC2 | |
| SCHEMBL2780605 | 0.73 | CNR2 (0.64) | CNR2ANPEPPOLBHDAC1HDAC2 | |
| SCHEMBL13196500 | 0.72 | CNR2 (0.52) | CNR2ANPEPPOLBCRHR1 | |
| SCHEMBL2781149 | 0.72 | CNR2 (0.53) | CNR2ANPEPPOLBHDAC1HDAC2 | |
| SCHEMBL2780539 | 0.72 | CNR2 (0.53) | CNR2ANPEPPOLBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | claimed |