Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828876 | 0.80 | LMNA (0.46) | LMNAALDH1A1TSHRHTTANPEP | |
| SCHEMBL2780482 | 0.79 | ALDH1A1 (0.37) | LMNAALDH1A1TSHRL3MBTL1ANPEP | |
| SCHEMBL2781466 | 0.79 | ALDH1A1 (0.37) | LMNAALDH1A1TSHRL3MBTL1ANPEP | |
| SCHEMBL2780477 | 0.79 | ALDH1A1 (0.37) | LMNAALDH1A1TSHRL3MBTL1ANPEP | |
| SCHEMBL2780834 | 0.78 | CNR2 (0.47) | ANPEP | |
| SCHEMBL13196497 | 0.78 | ALDH1A1 (0.34) | LMNAALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL2781219 | 0.78 | ALDH1A1 (0.34) | LMNAALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL2783324 | 0.78 | ALDH1A1 (0.34) | LMNAALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL2781759 | 0.73 | CNR2 (0.54) | LMNAALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL13196415 | 0.73 | CNR2 (0.56) | LMNAALDH1A1TSHRHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |