Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871594 | 0.82 | ENPP2 (0.48) | ALDH1A1KMT2AENPP2CYP1A2CYP1A1 | |
| SCHEMBL1332411 | 0.82 | — | — | |
| Water SCHEMBL27932616 | 0.82 | ENPP2 (0.48) | ALDH1A1KMT2AENPP2CYP1A2CYP1A1 | |
| SCHEMBL31402005 | 0.82 | — | — | |
| Benzene SCHEMBL7517467 | 0.82 | ENPP2 (0.48) | ALDH1A1KMT2AENPP2CYP1A2CYP1A1 | |
| SCHEMBL37831 | 0.82 | — | — | |
| SCHEMBL1921814 | 0.82 | — | — | |
| SCHEMBL1331365 | 0.82 | — | — | |
| Benzene SCHEMBL28804146 | 0.82 | ENPP2 (0.48) | ALDH1A1KMT2AENPP2CYP1A2CYP1A1 | |
| Methyl Alcohol SCHEMBL7457949 | 0.81 | ENPP2 (0.48) | ALDH1A1KMT2AENPP2CYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101786966-A | New preparation technology of p-nitro phenylacetonitrile | HUAIYIN TEACHER COLLEGE | 2010-07-28 | — | — | CN | disclosed |