Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.39 |
| ▸ | ARG2 | P78540 | 4/20 | 0.38 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL30472848 | 1.00 | GSR (0.57) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL28419849 | 0.97 | GSR (0.54) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL27898144 | 0.89 | GSR (0.54) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL27895871 | 0.87 | GSR (0.51) | GSRDPP7DPP8DPP9CYP1A2 | |
| Lysine SCHEMBL29981026 | 0.87 | GSR (0.51) | GSRDPP7DPP8DPP9CYP1A2 | |
| Lysine SCHEMBL30335781 | 0.87 | GSR (0.51) | GSRDPP7DPP8DPP9CYP1A2 | |
| Lysine SCHEMBL28979846 | 0.87 | GSR (0.51) | GSRDPP7DPP8DPP9CYP1A2 | |
| Glutamic Acid SCHEMBL31120738 | 0.84 | CYP1A2 (0.53) | GSRDPP8DPP9CYP1A2BLM | |
| D-Glutamate SCHEMBL28160914 | 0.84 | CYP1A2 (0.53) | GSRDPP8DPP9CYP1A2BLM | |
| Lysine SCHEMBL31241249 | 0.84 | GSR (0.51) | GSRDPP7DPP8DPP9ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624639-A | Preparation method and preparation system of cellulose solution | 山东中科恒联生物基材料有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117089937-A | Natural polymer conductive fiber and preparation method and application thereof | 中国科学院化学研究所 | 2023-11-21 | — | — | CN | disclosed |
| CN-116789990-A | Biomass microsphere and preparation method and application thereof | 中国科学院化学研究所 | 2023-09-22 | — | — | CN | disclosed |
| CN-116712787-A | Recovery method and recovery device for solvent for preparing regenerated cellulose material | 山东中科恒联生物基材料有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116284844-A | Natural polymer micro-nano functional material and preparation method and application thereof | 中国科学院化学研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-110982054-B | Composite catalyst for catalytically synthesizing polycarbonate and method for catalytically synthesizing polycarbonate | 中国科学院过程工程研究所 | 2021-03-12 | — | — | CN | disclosed |
| CN-110982054-A | Composite catalyst for catalytically synthesizing polycarbonate and method for catalytically synthesizing polycarbonate | 中国科学院过程工程研究所 | 2020-04-10 | — | — | CN | disclosed |
| CN-102060831-B | Method for separating mixed tocopherols from plant oil deodorizer condensates | UNIV ZHEJIANG | 2012-08-29 | — | — | CN | disclosed |
| CN-102060831-A | Method for separating mixed tocopherols from plant oil deodorizer condensates | UNIV ZHEJIANG | 2011-05-18 | — | — | CN | disclosed |