Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | ARG1 | P05089 | 3/20 | 0.36 |
| ▸ | ARG2 | P78540 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28979846 | 0.95 | GSR (0.51) | GSRDPP7DPP8DPP9GNAI3 | |
| Lysine SCHEMBL27895871 | 0.95 | GSR (0.51) | GSRDPP7DPP8DPP9GNAI3 | |
| Lysine SCHEMBL29981026 | 0.95 | GSR (0.51) | GSRDPP7DPP8DPP9GNAI3 | |
| Lysine SCHEMBL30335781 | 0.95 | GSR (0.51) | GSRDPP7DPP8DPP9GNAI3 | |
| Lysine SCHEMBL30472848 | 0.89 | GSR (0.57) | GSRDPP7DPP8DPP9GNAI3 | |
| Lysine SCHEMBL27808554 | 0.89 | GSR (0.57) | GSRDPP7DPP8DPP9GNAI3 | |
| Glutamic Acid SCHEMBL31454133 | 0.86 | SLC1A2 (0.49) | GSRSLC1A2SLC1A1SLC1A3GRIK1 | |
| Lysine SCHEMBL28419849 | 0.86 | GSR (0.54) | GSRDPP7DPP8DPP9GNAI3 | |
| D-Glutamate SCHEMBL28179361 | 0.86 | SLC1A2 (0.49) | GSRSLC1A2SLC1A1SLC1A3GRIK1 | |
| Serine SCHEMBL30913268 | 0.86 | SLC1A2 (0.43) | GSRDPP7SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107163377-B | A kind of Antibacterial polypropylene composition and preparation method thereof, application | 勤业工业（龙南）有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-107163377-A | A kind of Antibacterial polypropylene composition and preparation method thereof, application | 浙江帝恒实业有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-103046055-B | Imidazolyl lysine salt ionic liquid is as the application of iron and steel inhibiter | SICHUAN UNIVERSITY OF SCIENCE & ENGINEERING (CN) | 2015-11-04 | — | — | CN | claimed |
| CN-103046055-A | Imidazolyl lysine salt ionic liquid steel corrosion inhibitor and application thereof | UNIV SICHUAN SCI & ENG | 2013-04-17 | — | — | CN | claimed |
| CN-107163377-B | A kind of Antibacterial polypropylene composition and preparation method thereof, application | 勤业工业（龙南）有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-107163377-A | A kind of Antibacterial polypropylene composition and preparation method thereof, application | 浙江帝恒实业有限公司 | 2017-09-15 | — | — | CN | disclosed |
| CN-103046055-B | Imidazolyl lysine salt ionic liquid is as the application of iron and steel inhibiter | SICHUAN UNIVERSITY OF SCIENCE & ENGINEERING (CN) | 2015-11-04 | — | — | CN | disclosed |
| CN-104532254-A | Composite ionic liquid steel corrosion inhibitor and application | UNIV TIANJIN POLYTECHNIC | 2015-04-22 | — | — | CN | disclosed |
| CN-103046055-A | Imidazolyl lysine salt ionic liquid steel corrosion inhibitor and application thereof | UNIV SICHUAN SCI & ENG | 2013-04-17 | — | — | CN | disclosed |