Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090076 | 0.80 | ALDH1A1 (0.43) | NPSR1TSHRLMNAHTTHDAC1 | |
| SCHEMBL27787149 | 0.78 | GHSR (0.44) | TSHRMAPK1LMNAHTTHDAC1 | |
| SCHEMBL3097691 | 0.77 | ALDH1A1 (0.46) | NPSR1TSHRLMNAHTTHDAC1 | |
| SCHEMBL27787115 | 0.72 | ALDH1A1 (0.42) | NPSR1TSHRMAPK1LMNAHTT | |
| SCHEMBL27808958 | 0.71 | ALDH1A1 (0.40) | NPSR1TSHRMAPK1LMNAHTT | |
| SCHEMBL3103210 | 0.69 | HDAC1 (0.40) | NPSR1TSHRMAPK1LMNAHTT | |
| SCHEMBL3103202 | 0.69 | HDAC1 (0.40) | NPSR1TSHRMAPK1LMNAHTT | |
| SCHEMBL10677120 | 0.69 | ALDH1A1 (0.44) | NPSR1TSHRLMNAHTTHDAC1 | |
| SCHEMBL27787111 | 0.68 | ALDH1A1 (0.41) | NPSR1TSHRLMNAHTTMEN1 | |
| SCHEMBL10677114 | 0.67 | ALDH1A1 (0.46) | NPSR1TSHRLMNAHTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |