Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278669 | 0.89 | — | — | |
| SCHEMBL27646301 | 0.82 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL7259993 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL7860936 | 0.75 | MCHR1 (0.30) | — | |
| SCHEMBL7867503 | 0.75 | MCHR1 (0.30) | — | |
| SCHEMBL8189724 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL2226184 | 0.74 | CYP1A2 (0.32) | ALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL1271011 | 0.73 | KDM4E (0.30) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4266561 | 0.72 | ME2 (0.34) | KDM4EMAPTMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4428378 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102325550-A | Combination of photodynamic therapy and anti-VEGF agents in the treatment of unwanted choroidal neovasculature | QUADRA LOGIC TECH INC | 2012-01-18 | — | — | CN | disclosed |
| CN-101973999-A | Trimethoxysulfydrylporphyrin with carbon chain length being 6 | UNIV NORTHWEST NORMAL | 2011-02-16 | — | — | CN | disclosed |