Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.67 |
| ▸ | PPARD | Q03181 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448537 | 0.89 | ADORA3 (0.67) | ADORA3ADORA2AADORA1PPARDPPARG | |
| SCHEMBL30411668 | 0.89 | NPC1 (0.55) | ADORA3ADORA2AADORA1PPARDPPARG | |
| SCHEMBL20547189 | 0.89 | ADORA3 (0.57) | ADORA3ADORA2AADORA1PPARDPPARG | |
| SCHEMBL20547426 | 0.89 | NPC1 (0.68) | ADORA3ADORA2AADORA1YTHDC1NPC1 | |
| SCHEMBL30411200 | 0.86 | NPC1 (0.58) | ADORA3ADORA2AADORA1YTHDC1NPC1 | |
| SCHEMBL20547489 | 0.86 | YTHDC1 (0.61) | ADORA3ADORA2AADORA1PPARDPPARG | |
| SCHEMBL1501479 | 0.86 | NPC1 (0.73) | ADORA3ADORA2AADORA1YTHDC1NPC1 | |
| SCHEMBL29659561 | 0.86 | NPC1 (0.73) | ADORA3ADORA2AADORA1YTHDC1NPC1 | |
| SCHEMBL21967859 | 0.84 | YTHDC1 (0.59) | ADORA3ADORA2AADORA1YTHDC1NPC1 | |
| SCHEMBL20547488 | 0.83 | YTHDC1 (0.60) | ADORA3ADORA2AADORA1YTHDC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801970-A | Adenosine derivatives, method for synthesizing the same, and pharmaceutical composition for preventing and treating inflammatory diseases comprising the same as an active ingredient | FM THERAPEUTICS CO LTD | 2010-08-11 | — | — | CN | claimed |
| CN-101801970-A | Adenosine derivatives, method for synthesizing the same, and pharmaceutical composition for preventing and treating inflammatory diseases comprising the same as an active ingredient | FM THERAPEUTICS CO LTD | 2010-08-11 | — | — | CN | disclosed |