Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 6/20 | 0.58 |
| ▸ | PDE4A | P27815 | 13/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809372 | 0.89 | TPH1 (0.59) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27829761 | 0.86 | TPH1 (0.58) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL309142 | 0.81 | TPH1 (0.78) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL308500 | 0.81 | TPH1 (0.78) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL309040 | 0.79 | TPH1 (0.60) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL309041 | 0.79 | TPH1 (0.60) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27809368 | 0.79 | TPH1 (0.60) | TPH1PDE4A | |
| SCHEMBL307423 | 0.75 | TPH1 (0.81) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL307424 | 0.75 | TPH1 (0.81) | TPH1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL869240 | 0.74 | TPH1 (0.74) | TPH1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083454-A | Methods for diagnosing, preventing and treating bone mass disorders | UNIV COLUMBIA | 2011-06-01 | — | — | CN | disclosed |