Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118929 | 0.92 | ANPEP (0.42) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL10443784 | 0.91 | SLC15A1 (0.46) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL2478309 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL28790921 | 0.89 | SLC15A1 (0.50) | SLC15A1LTA4HSLC1A3SLC1A1ALPI | |
| SCHEMBL27715040 | 0.88 | ANPEP (0.40) | ANPEPRNPEPDNPEPSLC15A1CAPN1 | |
| SCHEMBL27809380 | 0.88 | CAPN1 (0.39) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL6825539 | 0.87 | ANPEP (0.43) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL8744670 | 0.87 | SLC1A3 (0.41) | ANPEPRNPEPDNPEPCTSBSLC1A3 | |
| SCHEMBL11433447 | 0.86 | SLC1A1 (0.41) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL7938097 | 0.85 | ANPEP (0.38) | ANPEPRNPEPDNPEPCAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083499-A | Combination therapy of a type II anti-CD20 antibody with a proteasome inhibitor | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |