Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383639 | 0.94 | ANPEP (0.40) | ANPEPRNPEPDNPEPCAPN1SLC15A1 | |
| SCHEMBL27809385 | 0.87 | ANPEP (0.48) | ANPEPRNPEPDNPEPCAPN1SLC15A1 | |
| SCHEMBL6830232 | 0.87 | ANPEP (0.42) | ANPEPRNPEPDNPEPLTA4HGPR88 | |
| SCHEMBL10443784 | 0.81 | SLC15A1 (0.46) | ANPEPRNPEPDNPEPCAPN1SLC15A1 | |
| SCHEMBL28118929 | 0.80 | ANPEP (0.42) | ANPEPRNPEPDNPEPCAPN1SLC15A1 | |
| SCHEMBL8586811 | 0.79 | CTSB (0.47) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL3660974 | 0.79 | ANPEP (0.44) | ANPEPRNPEPDNPEPSLC15A1LTA4H | |
| SCHEMBL27715040 | 0.78 | ANPEP (0.40) | ANPEPRNPEPDNPEPCAPN1SLC15A1 | |
| SCHEMBL2478309 | 0.78 | ANPEP (0.40) | ANPEPRNPEPDNPEPCAPN1SLC15A1 | |
| SCHEMBL7420644 | 0.77 | ANPEP (0.43) | ANPEPRNPEPDNPEPCAPN1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389624-A1 | Phosphorous-containing cysteine and serine protease inhibitors | CEPHALON, INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-0871454-B1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-0871454-A4 | — | — | 1998-11-25 | — | — | EP | disclosed |
| EP-0871454-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5639732-A | FOR TREATING NERVOUS SYSTEM DISORDERS OR AS ANTIINFLAMMATORY AGENT | CEPHALON, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1997003679-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-02-06 | — | — | WO | disclosed |