Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131296 | 1.00 | TPH1 (0.61) | TPH1 | |
| SCHEMBL1873078 | 0.87 | TPH1 (0.67) | TPH1 | |
| SCHEMBL1872985 | 0.85 | TPH1 (0.56) | TPH1 | |
| SCHEMBL1869997 | 0.83 | TPH1 (0.61) | TPH1 | |
| SCHEMBL20274857 | 0.77 | TPH1 (0.60) | TPH1 | |
| SCHEMBL3412957 | 0.75 | TPH1 (0.61) | TPH1 | |
| SCHEMBL322334 | 0.75 | TPH1 (1.00) | TPH1 | |
| SCHEMBL307612 | 0.75 | TPH1 (1.00) | TPH1 | |
| SCHEMBL307611 | 0.75 | TPH1 (1.00) | TPH1 | |
| SCHEMBL1877770 | 0.75 | TPH1 (0.49) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083454-A | Methods for diagnosing, preventing and treating bone mass disorders | UNIV COLUMBIA | 2011-06-01 | — | — | CN | disclosed |