Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452971 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL29452981 | 0.81 | — | — | |
| SCHEMBL4875493 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL680856 | 0.70 | CDK2 (0.55) | ALDH1A1KDM4ECDK2RXFP1GAA | |
| SCHEMBL29906262 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL9990576 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL4924100 | 0.70 | KDM4E (0.48) | ALDH1A1KDM4ECDK2HSD17B10 | |
| Purine SCHEMBL28067559 | 0.69 | ALDH1A1 (0.37) | ALDH1A1KDM4ECDK2RXFP1 | |
| SCHEMBL27695978 | 0.69 | CDK2 (0.47) | ALDH1A1KDM4ECDK2RXFP1 | |
| SCHEMBL6385068 | 0.69 | QPCT (0.50) | ALDH1A1KDM4ECDK2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102369218-A | Anti-fcrh5 antibodies and immunoconjugates and methods of use | GENENTECH INC | 2012-03-07 | — | — | CN | disclosed |
| CN-101802013-A | Humanized anti-CD 79B antibodies and immunoconjugates and methods of use | GENENTECH INC | 2010-08-11 | — | — | CN | disclosed |
| CN-101802012-A | anti-CD 79B antibodies and immunoconjugates and methods of use | GENENTECH INC | 2010-08-11 | — | — | CN | disclosed |