Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452971 | 0.90 | ALDH1A1 (0.63) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL4924100 | 0.81 | KDM4E (0.48) | ALDH1A1KDM4ECDK2HSD17B10 | |
| SCHEMBL27809463 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL680856 | 0.78 | CDK2 (0.55) | ALDH1A1KDM4ECDK2RXFP1ADORA2A | |
| SCHEMBL28833452 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Hydrochloric Acid SCHEMBL4456682 | 0.77 | CDK2 (0.54) | ALDH1A1KDM4ECDK2RXFP1ADORA2A | |
| SCHEMBL6385068 | 0.76 | QPCT (0.50) | ALDH1A1KDM4ECDK2ADORA2AADORA3 | |
| SCHEMBL9990576 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL29906262 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL5425282 | 0.74 | ADORA2A (0.49) | ALDH1A1KDM4ECDK2RXFP1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118957041-A | Method for determining polymer sequences | 牛津纳米孔科技公开有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118773294-A | Analysis method, analysis system and nanopore measurement and analysis system | 牛津楠路珀尔科技股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112703256-B | Method for determining polymer sequences | 牛津纳米孔科技公开有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-110546655-B | Machine learning analysis of nanopore measurements | 牛津楠路珀尔科技股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-109475593-A | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | 豪夫迈·罗氏有限公司 | 2019-03-15 | — | — | CN | disclosed |
| US-7449470-B2 | Substituted pyrimidines as ligands of adenosine receptors | UNIVERSITEIT LEIDEN (NL) | 2008-11-11 | — | — | US | disclosed |
| US-20070032510-A1 | Substituted pyrimidines as ligands of adenosine receptors | UNIVERSITEIT LEIDEN (NL) | 2007-02-08 | — | — | US | disclosed |
| CN-1837231-A | Immunomodulatory steroids, in particular the hemihydrate of 16, alpha-bromoepiandrosterone | HOLLIS EDEN PHARMACEUTICALS (US) | 2006-09-27 | — | — | CN | disclosed |
| EP-1667985-A1 | SUBSTITUTED PYRIMIDINES AS LIGANDS OF ADENOSINE RECEPTORS | Universiteit Leiden (NL) | 2006-06-14 | — | — | EP | disclosed |
| CN-1243767-C | Immunomodulatory steroids, in particular hemihydrate of 16 alpha-bromoepiandrosterone | HOLLIS EDEN PHARMACEUTICALS (US) | 2006-03-01 | — | — | CN | disclosed |
| WO-2005033084-A1 | SUBSTITUTED PYRIMIDINES AS LIGANDS OF ADENOSINE RECEPTORS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | disclosed |
| CN-1355809-A | Immunomodulatory steroids, in particular hemihydrate of 16 alpha-bromoepiandrosterone | HOLLIS EDEN PHARMACEUTICALS (US) | 2002-06-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032510-A1 | Substituted pyrimidines as ligands of adenosine receptors | ADORA2A, ADORA3, ADORA1 | ALDH1A1 852/4885KDM4E 4307/4885CDK2 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.