Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784442 | 0.86 | ALDH1A1 (0.40) | FFAR4ALDH1A1SMN1; SMN2SIRT2MAPT | |
| SCHEMBL27788398 | 0.85 | TP53 (0.40) | SMN1; SMN2MAPTALOX5TSHRNPC1 | |
| SCHEMBL27809485 | 0.84 | TRPV1 (0.41) | FFAR4ALDH1A1SMN1; SMN2SIRT2MAPT | |
| SCHEMBL27809423 | 0.84 | TRPV1 (0.43) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL27787503 | 0.77 | TRPV1 (0.44) | — | |
| SCHEMBL27809613 | 0.76 | MEN1 (0.39) | ALDH1A1SMN1; SMN2SIRT2MAPTKDM4E | |
| SCHEMBL2818112 | 0.75 | ALDH1A1 (0.41) | FFAR4ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27787586 | 0.74 | ALDH1A1 (0.40) | FFAR4ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL28784443 | 0.73 | TRPV1 (0.51) | — | |
| SCHEMBL27787523 | 0.73 | TRPV1 (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101796036-A | 5-Phenylisoxazole-3-carboxamide derivatives as TRPV1 modulators | ORGANON NV | 2010-08-04 | — | — | CN | disclosed |