Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856478 | 0.83 | IDO1 (0.48) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL4975059 | 0.83 | IDO1 (0.49) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL3900469 | 0.83 | IDO1 (0.49) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL10791552 | 0.78 | CYP2C9 (0.54) | CYP2C9ESR2MAPTLMNAALDH1A1 | |
| Bicarbonate SCHEMBL1719769 | 0.78 | IDO1 (0.51) | IDO1CYP2C9MAPTLMNAALDH1A1 | |
| SCHEMBL8025867 | 0.77 | CYP2C9 (0.59) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL260852 | 0.77 | CYP2C9 (0.59) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL2166886 | 0.77 | ESR2 (0.69) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL9264511 | 0.77 | ESR2 (0.69) | IDO1CYP2C9ESR2MAPTLMNA | |
| SCHEMBL9256924 | 0.77 | IDO1 (0.56) | IDO1CYP2C9ESR2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101781196-B | Method for preparing 4-(4-chlorphenyl)-cyclohexyl-1-formic acid | WUHAN TITON BIOTECH LTD | 2013-11-27 | — | — | CN | claimed |
| CN-101781196-A | Method for preparing 4-(4- chlorphenyl)-Ch cyclohexyl-1-formic acid | WUHAN TITON BIOTECH LTD | 2010-07-21 | — | — | CN | claimed |
| CN-104628555-B | A kind of synthetic method of pharmaceutical intermediate 4-(4-chlorphenyl) cyclohexyl-1-formic acid | 烟台蓓丰医药科技有限公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-104628555-A | Synthesis method of drug intermediate 4-(4-chlorphenyl) cyclohexyl-1-formic acid | YANTAI BIOFENGS PHARM TECH CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-101781196-B | Method for preparing 4-(4-chlorphenyl)-cyclohexyl-1-formic acid | WUHAN TITON BIOTECH LTD | 2013-11-27 | — | — | CN | disclosed |
| CN-101781196-A | Method for preparing 4-(4- chlorphenyl)-Ch cyclohexyl-1-formic acid | WUHAN TITON BIOTECH LTD | 2010-07-21 | — | — | CN | disclosed |