Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709064 | 0.91 | ESR1 (0.67) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9458998 | 0.86 | NPC1 (0.64) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL16859558 | 0.86 | ESR1 (0.65) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL30316301 | 0.86 | NPC1 (0.64) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL18053288 | 0.85 | ESR1 (0.59) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL11527051 | 0.85 | HRH3 (0.64) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL14549028 | 0.85 | ESR1 (0.59) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL7889086 | 0.85 | ESR1 (0.59) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9458337 | 0.84 | ALDH1A1 (0.67) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9458309 | 0.84 | ALDH1A1 (0.67) | ESR1LMNACYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759565-B | Method for synthesizing 6-halogeno-2-naphthoate | UNIV EAST CHINA SCIENCE & TECH | 2013-08-21 | — | — | CN | disclosed |
| CN-101759565-A | Method for synthesizing 6-halogeno-2-naphthoate | UNIV EAST CHINA SCIENCE & TECH | 2010-06-30 | — | — | CN | disclosed |