Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MET | P08581 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849226 | 0.87 | OGA (0.53) | ALDH1A1METHTTCASP1AKR1C3 | |
| SCHEMBL1953076 | 0.82 | MET (0.48) | ALDH1A1METNPC1POLBRAB9A | |
| SCHEMBL7226121 | 0.81 | ALDH1A1 (0.55) | ALDH1A1METNPC1POLBRAB9A | |
| SCHEMBL26634053 | 0.81 | AKR1C3 (0.49) | ALDH1A1METNPC1POLBRAB9A | |
| SCHEMBL112749 | 0.81 | ALDH1A1 (0.58) | ALDH1A1METNPC1POLBRAB9A | |
| SCHEMBL3656138 | 0.81 | NPC1 (0.49) | ALDH1A1METNPC1POLBRAB9A | |
| SCHEMBL1954298 | 0.80 | MET (0.49) | ALDH1A1METNPC1POLBRAB9A | |
| Bromide SCHEMBL3658940 | 0.79 | NPC1 (0.47) | ALDH1A1METNPC1POLBRAB9A | |
| SCHEMBL27720626 | 0.79 | CYP1A2 (0.49) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL1515835 | 0.78 | ALDH1A1 (0.50) | ALDH1A1METNPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074857-A | Method for preparing crystallization organic semiconducting materials | 巴斯夫欧洲公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-107004768-A | Organic semiconductor composition containing a liquid medium | 巴斯夫欧洲公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-103936743-A | Salts Of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- Imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide And Processes Related To Preparing The Same | INCYTE CORP | 2014-07-23 | — | — | CN | disclosed |
| CN-102083814-B | Salts of 2-fluoro-N-methyl-4- [7- (quinolin-6-ylmethyl) imidazo [1,2-b ] [1,2,4] triazin-2-yl ] benzamide and processes related thereto | INCYTE CORP | 2014-04-23 | — | — | CN | disclosed |
| CN-102083814-A | Salts of 2-fluoro-N-methyl-4- [7- (quinolin-6-ylmethyl) imidazo [1,2-b ] [1,2,4] triazin-2-yl ] benzamide and processes related thereto | INCYTE CORP | 2011-06-01 | — | — | CN | disclosed |
| CN-102083794-A | Urea compounds as gamma secretase modulators | AMGEN INC | 2011-06-01 | — | — | CN | disclosed |