Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809704 | 1.00 | KMT2A (0.49) | KMT2ASMN1; SMN2CFDPLGPLAU | |
| SCHEMBL1990399 | 0.89 | KMT2A (0.47) | KMT2ASMN1; SMN2FFAR1FFAR4CTSA | |
| SCHEMBL1990402 | 0.89 | KMT2A (0.47) | KMT2ASMN1; SMN2FFAR1FFAR4CTSA | |
| SCHEMBL1989783 | 0.85 | KMT2A (0.44) | KMT2ASMN1; SMN2FFAR1FFAR4CTSA | |
| SCHEMBL2167632 | 0.84 | KMT2A (0.47) | KMT2ASMN1; SMN2FOLH1PTGER1 | |
| SCHEMBL2166135 | 0.84 | KMT2A (0.47) | KMT2ASMN1; SMN2FOLH1PTGER1 | |
| SCHEMBL1990350 | 0.84 | PTGER1 (0.51) | KMT2ASMN1; SMN2FFAR1FFAR4CTSA | |
| SCHEMBL1783943 | 0.84 | KMT2A (0.47) | KMT2ASMN1; SMN2FOLH1PTGER1 | |
| SCHEMBL1990348 | 0.84 | PTGER1 (0.51) | KMT2ASMN1; SMN2FFAR1FFAR4CTSA | |
| SCHEMBL27809813 | 0.82 | MAOB (0.41) | KMT2ASMN1; SMN2CFDPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089262-A | Derivatives of 3- (2-hydroxy-5-methylphenyl) -N, N-diisopropyl-3-amphetamine and methods of use thereof | CONCERT PHARMACEUTICALS INC | 2011-06-08 | — | — | CN | disclosed |