SCHEMBL27809706

SCHEMBL27809706

Cc1cc(CCc2ccc(Cc3ccc(O)cc3)cc2)ccc1O

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.68
ESR2 Q92731 4/20 0.68
IGF1R P08069 2/20 0.52
ALOX15 P16050 2/20 0.52
SLC28A3 Q9HAS3 1/20 0.50
LTA4H P09960 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GFER P55789 1/20 0.47
TMEM97 Q5BJF2 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3241376 0.94 ESR1 (0.63) ESR1ESR2IGF1RALOX15SLC28A3
SCHEMBL11177663 0.90 ESR1 (0.83) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL6234291 0.90 ESR1 (0.83) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL22500464 0.87 IGF1R (0.69) ESR1ESR2IGF1RALOX15SLC28A3
SCHEMBL28999062 0.87 SLC28A3 (0.67) ESR1ESR2IGF1RALOX15SLC28A3
SCHEMBL1924746 0.86 ESR1 (0.74) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL29720481 0.86 ESR1 (0.74) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL27625130 0.83 PTGS1 (0.65) ESR1ESR2SLC28A3LTA4HKDM4E
SCHEMBL8357015 0.82 ESR1 (0.69) ESR1ESR2ALOX15
SCHEMBL36509 0.82 ESR1 (1.00) ESR1ESR2ALOX15KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101809502-A Thick film resists AZ ELECTRONIC MATERIALS USA 2010-08-18 CN claimed
CN-101809502-A Thick film resists AZ ELECTRONIC MATERIALS USA 2010-08-18 CN disclosed