Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
| ▸ | IGF1R | P08069 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809706 | 0.94 | ESR1 (0.68) | ESR1ESR2IGF1RALOX15SLC28A3 | |
| SCHEMBL22500464 | 0.92 | IGF1R (0.69) | ESR1ESR2IGF1RALOX15SLC28A3 | |
| SCHEMBL28999062 | 0.92 | SLC28A3 (0.67) | ESR1ESR2IGF1RALOX15SLC28A3 | |
| SCHEMBL29720481 | 0.91 | ESR1 (0.74) | ESR1ESR2IGF1RALOX15KDM4E | |
| SCHEMBL1924746 | 0.91 | ESR1 (0.74) | ESR1ESR2IGF1RALOX15KDM4E | |
| SCHEMBL172708 | 0.86 | ESR1 (0.61) | ESR1ESR2IGF1RALOX15KDM4E | |
| SCHEMBL11177663 | 0.83 | ESR1 (0.83) | ESR1ESR2IGF1RALOX15KDM4E | |
| SCHEMBL6234291 | 0.83 | ESR1 (0.83) | ESR1ESR2IGF1RALOX15KDM4E | |
| SCHEMBL529618 | 0.83 | ESR1 (0.68) | ESR1ESR2IGF1RALOX15SLC28A3 | |
| SCHEMBL68664 | 0.83 | ESR1 (0.68) | ESR1ESR2IGF1RALOX15SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | claimed |
| CN-101278239-B | Process for producing substrate with metal wiring | NIPPON ZEON CO | 2011-11-16 | — | — | CN | disclosed |
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| CN-101278239-A | Process for producing substrate with metal wiring | ZEON CORP (JP) | 2008-10-01 | — | — | CN | disclosed |