Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3018418 | 0.83 | SRC (0.37) | TYK2ALDH1A1 | |
| SCHEMBL3033938 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL3020621 | 0.78 | ALDH1A1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL15005722 | 0.77 | HDAC8 (0.32) | TYK2ALDH1A1HSD17B10 | |
| SCHEMBL3798658 | 0.77 | GUSB (0.30) | — | |
| SCHEMBL27964858 | 0.77 | — | — | |
| SCHEMBL3798656 | 0.77 | NPC1 (0.31) | — | |
| SCHEMBL15005724 | 0.76 | ALOX15 (0.37) | TYK2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3756501 | 0.71 | NPC1 (0.33) | TYK2KDM4EALDH1A1 | |
| SCHEMBL3032674 | 0.70 | SRC (0.38) | TYK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801965-B | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2014-07-30 | — | — | CN | claimed |
| CN-101801965-A | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-08-11 | — | — | CN | claimed |
| CN-101801965-B | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-101801965-A | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-08-11 | — | — | CN | disclosed |