Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | HTR5A | P47898 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003039 | 0.84 | HDAC6 (0.46) | MMP2HTR5AMMP9TSHRKDM4E | |
| SCHEMBL27840246 | 0.81 | — | — | |
| SCHEMBL11318343 | 0.78 | SRC (0.35) | KDM4ECCR1HTTCCR5CCR8 | |
| SCHEMBL5459975 | 0.77 | MAPT (0.48) | MMP2MMP9TSHRKDM4EGMNN | |
| SCHEMBL3145084 | 0.77 | RAB9A (0.53) | MMP2HTR5AMMP9TSHRKDM4E | |
| SCHEMBL6225626 | 0.77 | KDM4E (0.48) | MMP2HTR5AMMP9TSHRKDM4E | |
| SCHEMBL28317851 | 0.77 | RET (0.35) | MMP2MMP9LMNAMAPTHTT | |
| SCHEMBL28707626 | 0.77 | MMP2 (0.48) | MMP2MMP9TSHRKDM4EGMNN | |
| SCHEMBL16825440 | 0.77 | KDM4E (0.44) | MMP2HTR5AMMP9TSHRKDM4E | |
| SCHEMBL27958707 | 0.77 | KDM4E (0.44) | KDM4ELMNACYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110270295-B | Preparation method of amino-substituted benzopyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-110270295-A | Preparation method of amino-substituted phenylpropylpyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-110270295-B | Preparation method of amino-substituted benzopyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-110270295-B | Preparation method of amino-substituted benzopyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-110270295-A | Preparation method of amino-substituted phenylpropylpyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-110270295-A | Preparation method of amino-substituted phenylpropylpyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-109562169-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563167-A | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109452288-A | The composition and its method of administration for preventing and treating great Jiang bacterial wilt | 王兴翠 | 2019-03-12 | — | — | CN | disclosed |
| CN-103958508-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-102083438-A | Quenolines and related analogs as sirtuin modulators | SIRTRIS PHARMACEUTICALS INC | 2011-06-01 | — | — | CN | disclosed |
| CN-102036561-A | Protein kinase modulators | CYLENE PHARMACEUTICALS INC | 2011-04-27 | — | — | CN | disclosed |