Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810521 | 0.89 | BTK (0.36) | SMN1; SMN2RECQL | |
| SCHEMBL27788942 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2RECQL | |
| SCHEMBL27266929 | 0.74 | MEN1 (0.33) | RECQLTSHR | |
| SCHEMBL27726473 | 0.73 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL27726471 | 0.71 | ADRB2 (0.31) | SMN1; SMN2 | |
| SCHEMBL28784554 | 0.70 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL27779427 | 0.69 | MAPK10 (0.34) | SMN1; SMN2 | |
| SCHEMBL18215491 | 0.68 | — | — | |
| SCHEMBL18667339 | 0.68 | — | — | |
| SCHEMBL9900646 | 0.68 | L3MBTL1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101808666-A | Combination of antimitotic and lasokinase inhibitors as anticancer therapy | SCHERING CORP | 2010-08-18 | — | — | CN | disclosed |