Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813405 | 0.89 | ALDH1A1 (0.52) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30309479 | 0.80 | KMT2A (0.61) | ALDH1A1POLBLMNASMN1; SMN2MAPT | |
| SCHEMBL4937576 | 0.80 | KMT2A (0.61) | ALDH1A1POLBLMNASMN1; SMN2MAPT | |
| SCHEMBL1020775 | 0.80 | ALDH1A1 (0.50) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL9426474 | 0.75 | KCNJ1 (0.57) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30309424 | 0.74 | HRH4 (0.59) | ALDH1A1POLBLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL4288250 | 0.74 | POLB (0.52) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30309443 | 0.74 | LMNA (0.53) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30065341 | 0.74 | ALDH1A1 (0.63) | ALDH1A1POLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL22405638 | 0.73 | ALDH1A1 (0.60) | ALDH1A1POLBLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101848899-A | N-benzyl, n' -arylcarbonylpiperazine derivatives as lxr modulators | ORGANON NV | 2010-09-29 | — | — | CN | disclosed |